TARGETED DELIVERY OF OXALIPLATIN VIA FOLATE-DECORATED NIOSOMAL NANOPARTICLES POTENTIATES RESISTANCE REVERSION OF COLON CANCER CELLS

Targeted delivery of oxaliplatin via folate-decorated niosomal nanoparticles potentiates resistance reversion of colon cancer cells

Background: Colorectal cancer (CRC) is a prevalent type of cancer, ranking third in incidence and fourth in cancer-related deaths globally.The increase in mortality rates related to colorectal cancer among younger patients is a cause for concern.Chemotherapy is the primary approach for palliative care in colon cancer, but the development of drug re

read more

Differential Response of Coral Assemblages to Thermal Stress Underscores the Complexity in Predicting Bleaching Susceptibility.

Coral bleaching events have been predicted to occur more frequently in the coming decades with global warming.The susceptibility of corals to bleaching during thermal stress episodes is dependent on many factors and an understanding of these underlying drivers is crucial for conservation management.In 2013, a mild bleaching episode ensued in respon

read more

Chronic heat stress inhibits glycogen synthesis through gga-miR-212-5p/GYS1 axis in the breast muscle of broilers

ABSTRACT: Studies have demonstrated that chronic heat stress can accelerate glycolysis, decrease glycogen content in muscle, and affect muscle quality.However, the consequences of chronic heat stress on glycogen synthesis, miRNA expression in pectoralis major (PM) muscle, and its regulatory functions remain unknown.In this study, Ski de fond - Acce

read more